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Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions

The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Moreno, Esther, Calvo, Alba, Schwartz, Juana, Navarro-Blasco, Iñigo, González-Peñas, Elena, Sanmartín, Carmen, Irache, Juan Manuel, Espuelas, Socorro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920985/
https://ncbi.nlm.nih.gov/pubmed/31766282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110607
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