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Improving In Vivo Brain Delivery of Monoclonal Antibody Using Novel Cyclic Peptides

Many proteins can be used to treat brain diseases; however, the presence of the blood–brain barrier (BBB) creates an obstacle to delivering them into the brain. Previously, various molecules were delivered through the paracellular pathway of the BBB via its modulation, using ADTC5 and HAV6 peptides....

Полное описание

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Библиографические подробности
Опубликовано в: :Pharmaceutics
Главные авторы: Ulapane, Kavisha R., Kopec, Brian M., Siahaan, Teruna J.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920923/
https://ncbi.nlm.nih.gov/pubmed/31683745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110568
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