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Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment

Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes have shown limited ability to protect DS. Therefore, the aim of this study is to...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Najlah, Mohammad, Said Suliman, Ammar, Tolaymat, Ibrahim, Kurusamy, Sathishkumar, Kannappan, Vinodh, Elhissi, Abdelbary M. A., Wang, Weiguang
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920821/
https://ncbi.nlm.nih.gov/pubmed/31739556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110610
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