GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways

Selenium nanoparticles (Se NPs) have attracted increasing interest in recent decades because of their anticancer, immunoregulation, and drug carrier functions. In this study, GE11 peptide-conjugated Se NPs (GE11-Se NPs), a nanosystem targeting EGFR over-expressed cancer cells, were synthesized for o...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Pi, Jiang, Jiang, Jinhuan, Cai, Huaihong, Yang, Fen, Jin, Hua, Yang, Peihui, Cai, Jiye, Chen, Zheng W.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920706/
https://ncbi.nlm.nih.gov/pubmed/29019267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1386729
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