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FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway

Forkhead box D3 (FOXD3), as a transcriptional repressor, is well known to be involved in the regulation of development. Although FoxD3 is associated with several cancers, its role in colon cancer and the underlying mechanism are still unclear. Here, we first showed that FOXD3 knockdown dramatically...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Kun, Guo, Qunfeng, Yang, Jun, Chen, Hui, Hu, Kewen, Zhao, Juan, Zheng, Shunxin, Pang, Xiufeng, Zhou, Sufang, Dang, Yongyan, Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354891/
https://ncbi.nlm.nih.gov/pubmed/27926503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13790
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