Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice

Kynurenic acid (KYNA), a glial-derived metabolite of tryptophan metabolism, is an antagonist of the alpha 7 nicotinic acetylcholine receptor and the glycine-binding site of N-methyl-d-aspartate (NMDA) receptors. Kynurenic acid levels are increased in both the brain and cerebrospinal fluid of several...

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Bibliografske podrobnosti
izdano v:Int J Tryptophan Res
Main Authors: Peyton, Lee, Oliveros, Alfredo, Tufvesson-Alm, Maximilian, Schwieler, Lilly, Starski, Phillip, Engberg, Göran, Erhardt, Sopie, Choi, Doo-Sup
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2019
Teme:
ISTRY 2018
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920585/
https://ncbi.nlm.nih.gov/pubmed/31896932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178646919891169
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