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Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice
Kynurenic acid (KYNA), a glial-derived metabolite of tryptophan metabolism, is an antagonist of the alpha 7 nicotinic acetylcholine receptor and the glycine-binding site of N-methyl-d-aspartate (NMDA) receptors. Kynurenic acid levels are increased in both the brain and cerebrospinal fluid of several...
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| Publicado no: | Int J Tryptophan Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920585/ https://ncbi.nlm.nih.gov/pubmed/31896932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178646919891169 |
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