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Stochastic Expansions Maintain the Clonal Stability of CD8(+) T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

CMV is an obligate and persistent intracellular pathogen that continually drives the production of highly differentiated virus-specific CD8(+) T cells in an Ag-dependent manner, a phenomenon known as memory inflation. Extensive proliferation is required to generate and maintain inflationary CD8(+) T...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Smith, Corinne J., Venturi, Vanessa, Quigley, Maire F., Turula, Holly, Gostick, Emma, Ladell, Kristin, Hill, Brenna J., Himelfarb, Danielle, Quinn, Kylie M., Greenaway, Hui Yee, Dang, Thurston H. Y., Seder, Robert A., Douek, Daniel C., Hill, Ann B., Davenport, Miles P., Price, David A., Snyder, Christopher M.
Format: Artigo
Jezik:Inglês
Izdano: AAI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920548/
https://ncbi.nlm.nih.gov/pubmed/31818981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900455
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