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Stochastic Expansions Maintain the Clonal Stability of CD8(+) T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

CMV is an obligate and persistent intracellular pathogen that continually drives the production of highly differentiated virus-specific CD8(+) T cells in an Ag-dependent manner, a phenomenon known as memory inflation. Extensive proliferation is required to generate and maintain inflationary CD8(+) T...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Smith, Corinne J., Venturi, Vanessa, Quigley, Maire F., Turula, Holly, Gostick, Emma, Ladell, Kristin, Hill, Brenna J., Himelfarb, Danielle, Quinn, Kylie M., Greenaway, Hui Yee, Dang, Thurston H. Y., Seder, Robert A., Douek, Daniel C., Hill, Ann B., Davenport, Miles P., Price, David A., Snyder, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920548/
https://ncbi.nlm.nih.gov/pubmed/31818981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900455
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