Mapping of Shigella flexneri’s tissue distribution and type III secretion apparatus activity during infection of the large intestine of guinea pigs

Shigella spp. are bacterial pathogens that invade the human colonic mucosa using a type III secretion apparatus (T3SA), a proteinaceous device activated upon contact with host cells. Active T3SAs translocate proteins that carve the intracellular niche of Shigella spp. Nevertheless, the activation st...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: Nigro, Giulia, Arena, Ellen T, Sachse, Martin, Moya-Nilges, Maryse, Marteyn, Benoit S, Sansonetti, Philippe J, Campbell-Valois, F-X
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920510/
https://ncbi.nlm.nih.gov/pubmed/31578543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftz054
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