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Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson’s disease mouse model

Focused ultrasound-enhanced intranasal (IN + FUS) delivery is a noninvasive approach that utilizes the olfactory pathway to administer pharmacological agents directly to the brain, allowing for a more homogenous distribution in targeted locations compared to IN delivery alone. However, whether such...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ji, Robin, Smith, Morgan, Niimi, Yusuke, Karakatsani, Maria E., Murillo, Maria F., Jackson-Lewis, Vernice, Przedborski, Serge, Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920380/
https://ncbi.nlm.nih.gov/pubmed/31852909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55294-5
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