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Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice

TLR4 is a transmembrane receptor of the innate immune system that recognizes LPS from gram-negative bacteria. Its stimulation induces pro-inflammatory responses and modulates adaptive immunity. Our aim is to determine the role of TLR4 in the activation and proliferation of T lymphocytes in the onset...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alibashe-Ahmed, Mohamed, Brioudes, Estelle, Reith, Walter, Bosco, Domenico, Berney, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920362/
https://ncbi.nlm.nih.gov/pubmed/31852918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55521-z
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