Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis

The chemotherapeutic drug cisplatin, which targets DNA, serves as one of the main staples in cancer treatment. Yet, the therapeutic application of cisplatin is limited by two major challenges: the occurrence of reversible and irreversible side effects due to non-specific toxicity, and the intrinsic...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Xie, Lihan, Rajpurkar, Asavari, Quarles, Ellen, Taube, Nicole, Rai, Akash S., Erba, Jake, Sliwinski, Benjamin, Markowitz, Moses, Jakob, Ursula, Knoefler, Daniela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920253/
https://ncbi.nlm.nih.gov/pubmed/31921667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01410
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