Multiple Functions and Mechanisms Underlying the Role of METTL3 in Human Cancers

Methyltransferase-like 3 (METTL3), a predominantly catalytic enzyme in the N(6)-methyladenosine (m(6)A) methyltransferase system, is dysregulated and plays a dual role (oncogene or tumor suppressor) in different human cancers. The expression and pro- or anticancer role of METTL3 in different cancers...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Zheng, Wenhui, Dong, Xiaoshen, Zhao, Yan, Wang, Shuo, Jiang, Haiyang, Zhang, Mingdi, Zheng, Xinyu, Gu, Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920212/
https://ncbi.nlm.nih.gov/pubmed/31921660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01403
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