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Roles of METTL3 in cancer: mechanisms and therapeutic targeting

N(6)-methyladenosine (m(6)A) is the most abundant mRNA modification and is catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is the sole catalytic subunit. Accumulating evidence in recent years reveals that METTL3 plays key roles in a variety of cancer types, eit...

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Détails bibliographiques
Publié dans:J Hematol Oncol
Auteurs principaux: Zeng, Chengwu, Huang, Wanxu, Li, Yangqiu, Weng, Hengyou
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457244/
https://ncbi.nlm.nih.gov/pubmed/32854717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00951-w
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