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A dimerization-based fluorogenic dye-aptamer module for RNA imaging in live cells
Live-cell imaging of RNA has remained a challenge because of the lack of naturally fluorescent RNAs. Recently developed RNA aptamers that can light-up small fluorogenic dyes could overcome this limitation, but they still suffer from poor brightness and photostability. Here, we propose a concept of c...
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| Опубликовано в: : | Nat Chem Biol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920041/ https://ncbi.nlm.nih.gov/pubmed/31636432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0381-8 |
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