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The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored. Here, we established an integrated screening strategy to discover lncRNAs implicated in neurotransmitter and synaptic vesicle release. With...

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Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Keihani, S., Kluever, V., Mandad, S., Bansal, V., Rahman, R., Fritsch, E., Gomes, L. Caldi, Gärtner, A., Kügler, S., Urlaub, H., Wren, J. D., Bonn, S., Rizzoli, S. O., Fornasiero, E. F.
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920028/
https://ncbi.nlm.nih.gov/pubmed/31897430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay2670
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