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The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored. Here, we established an integrated screening strategy to discover lncRNAs implicated in neurotransmitter and synaptic vesicle release. With...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Keihani, S., Kluever, V., Mandad, S., Bansal, V., Rahman, R., Fritsch, E., Gomes, L. Caldi, Gärtner, A., Kügler, S., Urlaub, H., Wren, J. D., Bonn, S., Rizzoli, S. O., Fornasiero, E. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920028/
https://ncbi.nlm.nih.gov/pubmed/31897430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay2670
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