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Evaluation of the STAT3 inhibitor GLG-302 for the prevention of estrogen receptor-positive and -negative mammary cancers

Signal transducer and activator of transcription 3 (STAT3) plays a key role in the transformation of normal cells to cancerous cells. Although inhibitors of STAT3 have been shown to suppress the growth of multiple cancer types in vitro and in vivo, such agents are of particular interest for the prev...

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Dades bibliogràfiques
Publicat a:Oncol Rep
Autors principals: Shoemaker, Robert H., Fox, Jennifer T., Juliana, M. Margaret, Moeinpour, Fariba L., Grubbs, Clinton J.
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918811/
https://ncbi.nlm.nih.gov/pubmed/31322250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7219
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