Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus

Balanced progenitor activities are crucial for the development and maintenance of high turn-over organs such as the esophagus. However, the molecular mechanisms regulating these progenitor activities in the esophagus remain to be elucidated. Here, we demonstrated that Yap is required for the prolife...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Bailey, Dominique D., Zhang, Yongchun, van Soldt, Benjamin J., Jiang, Ming, Suresh, Supriya, Nakagawa, Hiroshi, Rustgi, Anil K., Aceves, Seema S., Cardoso, Wellington V., Que, Jianwen
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918786/
https://ncbi.nlm.nih.gov/pubmed/31748205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.178855
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