Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus

Balanced progenitor activities are crucial for the development and maintenance of high turn-over organs such as the esophagus. However, the molecular mechanisms regulating these progenitor activities in the esophagus remain to be elucidated. Here, we demonstrated that Yap is required for the prolife...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Bailey, Dominique D., Zhang, Yongchun, van Soldt, Benjamin J., Jiang, Ming, Suresh, Supriya, Nakagawa, Hiroshi, Rustgi, Anil K., Aceves, Seema S., Cardoso, Wellington V., Que, Jianwen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918786/
https://ncbi.nlm.nih.gov/pubmed/31748205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.178855
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