Combinatorial genetic replenishments in myocardial and outflow tract tissues restore heart function in tnnt2 mutant zebrafish

Cardiac muscle troponin T (Tnnt2) mediates muscle contraction in response to calcium ion dynamics, and Tnnt2 mutations are associated with multiple types of cardiomyopathy. Here, we employed a zebrafish model to investigate the genetic replenishment strategies of using conditional and inducible prom...

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Dades bibliogràfiques
Publicat a:Biol Open
Autors principals: Liu, Lian, Fei, Fei, Zhang, Ranran, Wu, Fang, Yang, Qian, Wang, Feng, Sun, Shaoyang, Zhao, Hui, Li, Qiang, Wang, Lei, Wang, Youhua, Gui, Yonghao, Wang, Xu
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918781/
https://ncbi.nlm.nih.gov/pubmed/31796423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.046474
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