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High Resolution Imaging of DNA Methylation Dynamics using a Zebrafish Reporter

As one of the major epigenetic modifications, DNA methylation is constantly regulated during embryonic development, cell lineage commitment, and pathological processes. To facilitate real-time observation of DNA methylation, we generated a transgenic zebrafish reporter of DNA methylation (zebraRDM)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Ranran, Liu, Lian, Yao, Yuxiao, Fei, Fei, Wang, Feng, Yang, Qian, Gui, Yonghao, Wang, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511286/
https://ncbi.nlm.nih.gov/pubmed/28710355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05648-8
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