Longitudinal study revealing motor, cognitive and behavioral decline in a transgenic minipig model of Huntington's disease

Huntington's disease (HD) is an inherited devastating neurodegenerative disease with no known cure to date. Several therapeutic treatments for HD are in development, but their safety, tolerability and efficacy need to be tested before translation to bedside. The monogenetic nature of this disor...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Baxa, Monika, Levinska, Bozena, Skrivankova, Monika, Pokorny, Matous, Juhasova, Jana, Klima, Jiri, Klempir, Jiri, Motlík, Jan, Juhas, Stefan, Ellederova, Zdenka
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918771/
https://ncbi.nlm.nih.gov/pubmed/31704691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.041293
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