Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice

The number and quality of oocytes within the ovarian reserve largely determines fertility and reproductive lifespan in mammals. An oocyte-specific transcription factor cascade controls oocyte development, and some of these transcription factors, such as newborn ovary homeobox gene (NOBOX), are candi...

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Bibliographic Details
Published in:Development
Main Authors: Rodriguez, Amanda, Briley, Shawn M., Patton, Bethany K., Tripurani, Swamy K., Rajapakshe, Kimal, Coarfa, Cristian, Rajkovic, Aleksander, Andrieux, Alexandra, Dejean, Anne, Pangas, Stephanie A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918767/
https://ncbi.nlm.nih.gov/pubmed/31704792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.176701
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