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The RTK Interactome: Overview and Perspective on RTK Hetero-Interactions

Receptor tyrosine kinases (RTKs) play important roles in cell growth, motility, differentiation, and survival. These single-pass membrane proteins are grouped into subfamilies based on the similarity of their extracellular domains. They are generally thought to be activated by ligand binding, which...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Paul, Michael D., Hristova, Kalina
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918702/
https://ncbi.nlm.nih.gov/pubmed/30589534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.8b00467
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