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Subcellular NAMPT-mediated NAD(+) salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury
NAD(+) is a cofactor required for glycolysis, tricarboxylic acid cycle and complex I enzymatic reaction. In mammalian cells, NAD(+) is predominantly synthesized through the salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme. Previously, we demonstrated...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6917901/ https://ncbi.nlm.nih.gov/pubmed/31553812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14878 |
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