Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps

Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by type 2 inflammation with accumulation of activated group 2 innate lymphoid cells (ILC2s) and elevation of thymic stromal lymphopoietin (TSLP). A member of the TNF superfamily (TNFSF), TNFSF15, is known to induce the production of...

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Publicado no:Mucosal Immunol
Main Authors: Ogasawara, Noriko, Poposki, Julie A., Klingler, Aiko I., Tan, Bruce K., Hulse, Kathryn E., Stevens, Whitney W., Peters, Anju T., Grammer, Leslie C., Welch, Kevin C., Smith, Stephanie S., Conley, David B., Raviv, Joseph R., Soroosh, Pejman, Takano, Ken-ichi, Himi, Tetsuo, Kern, Robert C., Schleimer, Robert P., Kato, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917894/
https://ncbi.nlm.nih.gov/pubmed/31641233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0215-8
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