Thymic stromal lymphopoietin activity is increased in nasal polyps of chronic rhinosinusitis

BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with Th2-dominant inflammation. Thymic stromal lymphopoietin (TSLP) is a cytokine that triggers dendritic cell-mediated Th2 inflammatory responses and that enhances IL-1-dependent Th2 cytokine production in mast cells. Altho...

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Autors principals: Nagarkar, Deepti R., Poposki, Julie A., Tan, Bruce K., Comeau, Michael R., Peters, Anju T., Hulse, Kathryn E., Suh, Lydia A., Norton, James, Harris, Kathleen E., Grammer, Leslie C., Chandra, Rakesh K., Conley, David B., Kern, Robert C., Schleimer, Robert P., Kato, Atsushi
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759596/
https://ncbi.nlm.nih.gov/pubmed/23688414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.04.005
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