Thymic stromal lymphopoietin activity is increased in nasal polyps of chronic rhinosinusitis

BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with Th2-dominant inflammation. Thymic stromal lymphopoietin (TSLP) is a cytokine that triggers dendritic cell-mediated Th2 inflammatory responses and that enhances IL-1-dependent Th2 cytokine production in mast cells. Altho...

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Hlavní autoři: Nagarkar, Deepti R., Poposki, Julie A., Tan, Bruce K., Comeau, Michael R., Peters, Anju T., Hulse, Kathryn E., Suh, Lydia A., Norton, James, Harris, Kathleen E., Grammer, Leslie C., Chandra, Rakesh K., Conley, David B., Kern, Robert C., Schleimer, Robert P., Kato, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759596/
https://ncbi.nlm.nih.gov/pubmed/23688414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.04.005
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