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GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A
Excessive expression of subunit 1 of GIRK1 in ER(+) breast tumors is associated with reduced survival times and increased lymph node metastasis in patients. To investigate possible tumor-initiating properties, benign MCF10A and malign MCF7 mammary epithelial cells were engineered to overexpress GIRK...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6917815/ https://ncbi.nlm.nih.gov/pubmed/31848385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55683-w |
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