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Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure

Heart failure is the major cause of death for muscular dystrophy patients, however, the molecular pathomechanism remains unknown. Here, we show the detailed molecular pathogenesis of muscular dystrophy-associated cardiomyopathy in mice lacking the fukutin gene (Fktn), the causative gene for Fukuyama...

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Publicado en:Nat Commun
Main Authors: Ujihara, Yoshihiro, Kanagawa, Motoi, Mohri, Satoshi, Takatsu, Satomi, Kobayashi, Kazuhiro, Toda, Tatsushi, Naruse, Keiji, Katanosaka, Yuki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917736/
https://ncbi.nlm.nih.gov/pubmed/31848331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13623-2
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