The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis

Laminin-γ1 is required for early embryonic development; however, the need for laminin-γ1 synthesis in adulthood is unknown. A global and inducible mouse model of laminin-γ1 deficiency was generated to address this question. Genetic ablation of the Lamc1 gene in adult mice was rapidly lethal. Despite...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Fields, British, DeLaForest, Ann, Zogg, Mark, May, Jennifer, Hagen, Catherine, Komnick, Kristin, Wieser, Jon, Lundberg, Alexander, Weiler, Hartmut, Battle, Michele A., Carlson, Karen-Sue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917708/
https://ncbi.nlm.nih.gov/pubmed/31848396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55844-x
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