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The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis
Laminin-γ1 is required for early embryonic development; however, the need for laminin-γ1 synthesis in adulthood is unknown. A global and inducible mouse model of laminin-γ1 deficiency was generated to address this question. Genetic ablation of the Lamc1 gene in adult mice was rapidly lethal. Despite...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6917708/ https://ncbi.nlm.nih.gov/pubmed/31848396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55844-x |
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