Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade

Coronaries are essential for myocardial growth and heart function. Notch is crucial for mouse embryonic angiogenesis, but its role in coronary development remains uncertain. We show Jag1, Dll4 and activated Notch1 receptor expression in sinus venosus (SV) endocardium. Endocardial Jag1 removal blocks...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Travisano, Stanislao Igor, Oliveira, Vera Lucia, Prados, Belén, Grego-Bessa, Joaquim, Piñeiro-Sabarís, Rebeca, Bou, Vanesa, Gómez, Manuel J, Sánchez-Cabo, Fátima, MacGrogan, Donal, de la Pompa, José Luis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2019
Aiheet:
Developmental Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917494/
https://ncbi.nlm.nih.gov/pubmed/31789590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49977
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