Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade

Coronaries are essential for myocardial growth and heart function. Notch is crucial for mouse embryonic angiogenesis, but its role in coronary development remains uncertain. We show Jag1, Dll4 and activated Notch1 receptor expression in sinus venosus (SV) endocardium. Endocardial Jag1 removal blocks...

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Gepubliceerd in:eLife
Hoofdauteurs: Travisano, Stanislao Igor, Oliveira, Vera Lucia, Prados, Belén, Grego-Bessa, Joaquim, Piñeiro-Sabarís, Rebeca, Bou, Vanesa, Gómez, Manuel J, Sánchez-Cabo, Fátima, MacGrogan, Donal, de la Pompa, José Luis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2019
Onderwerpen:
Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917494/
https://ncbi.nlm.nih.gov/pubmed/31789590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49977
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