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DNA REPAIR FOOTPRINT UNCOVERS CONTRIBUTION OF DNA REPAIR MECHANISM TO MUTATIONAL SIGNATURES

Cancer genomes accumulate a large number of somatic mutations resulting from imperfection of DNA processing during normal cell cycle as well as from carcinogenic exposures or cancer related aberrations of DNA maintenance machinery. These processes often lead to distinctive patterns of mutations, cal...

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Bibliografiske detaljer
Udgivet i:Pac Symp Biocomput
Main Authors: Wojtowicz, Damian, Leiserson, Mark D.M., Sharan, Roded, Przytycka, Teresa M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917478/
https://ncbi.nlm.nih.gov/pubmed/31797602
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