Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis

Allelic variants of genes encoding for the Fc gamma receptors IIIA and IIA have been associated with the clinical response to cell‐depleting antibodies in lymphoma patients. Here, we tested the hypothesis that FCGR3A and FCGR2A high‐affinity polymorphisms predict clinical outcomes to alemtuzumab the...

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Dettagli Bibliografici
Pubblicato in:Ann Clin Transl Neurol
Autori principali: Keller, Christian W., Ruck, Tobias, McHugh, Donal, Pfeuffer, Steffen, Gross, Catharina C., Korsukewitz, Catharina, Melzer, Nico, Klotz, Luisa, Meuth, Sven G., Münz, Christian, Nimmerjahn, Falk, Wiendl, Heinz, Lünemann, Jan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917309/
https://ncbi.nlm.nih.gov/pubmed/31682087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50935
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