Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis

Allelic variants of genes encoding for the Fc gamma receptors IIIA and IIA have been associated with the clinical response to cell‐depleting antibodies in lymphoma patients. Here, we tested the hypothesis that FCGR3A and FCGR2A high‐affinity polymorphisms predict clinical outcomes to alemtuzumab the...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Keller, Christian W., Ruck, Tobias, McHugh, Donal, Pfeuffer, Steffen, Gross, Catharina C., Korsukewitz, Catharina, Melzer, Nico, Klotz, Luisa, Meuth, Sven G., Münz, Christian, Nimmerjahn, Falk, Wiendl, Heinz, Lünemann, Jan D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917309/
https://ncbi.nlm.nih.gov/pubmed/31682087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50935
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