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Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel

A significant factor contributing to poor survival rates for ovarian cancer patients is insensitivity of tumors to standard-of-care chemotherapy. In this study, we investigated the effect of claudin-4 expression on ovarian tumor cell apoptotic response to cisplatin and paclitaxel. We manipulated cla...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Breed, Christopher, Hicks, Douglas A., Webb, Patricia G., Galimanis, Carly E., Bitler, Benjamin G., Behbakht, Kian, Baumgartner, Heidi K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916652/
https://ncbi.nlm.nih.gov/pubmed/30606772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0451
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