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Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial

AIMS: The AleCardio trial aimed to characterize the efficacy and safety of peroxisome proliferator‐activated receptor‐αγ agonist aleglitazar in patients with type 2 diabetes mellitus and acute coronary syndrome. The trial terminated early because of futility and safety signals. We evaluated whether...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Main Authors: Koomen, Jeroen V., Heerspink, Hiddo J. L., Schrieks, Ilse C., Schwartz, Gregory G., Lincoff, A. Michael, Nicholls, Stephen J., Svensson, Anders, Wedel, Hans, Weichert, Arlette, Grobbee, Diederick E., Stevens, Jasper
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916612/
https://ncbi.nlm.nih.gov/pubmed/31468659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13862
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