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Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control
The protein quality control machinery of the endoplasmic reticulum (ERQC) ensures that client proteins are properly folded. ERQC substrates may be recognized as nonnative by the presence of exposed hydrophobic surfaces, free thiols, or processed N-glycans. How these features dictate which ERQC pathw...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6916506/ https://ncbi.nlm.nih.gov/pubmed/31662433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010450 |
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