Načítá se...

Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function

Cholesterol plays essential structural and signaling roles in mammalian cells, but too much cholesterol can cause cytotoxicity. Acyl-CoA:cholesterol acyltransferases 1 and 2 (ACAT1/2) convert cholesterol into its storage form, cholesteryl esters, regulating a key step in cellular cholesterol homeost...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Xu, Yanqing, Du, Ximing, Turner, Nigel, Brown, Andrew J., Yang, Hongyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916500/
https://ncbi.nlm.nih.gov/pubmed/31727739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011160
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!