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Cytoplasmic dsRNA induces the expression of OCT3/4 and NANOG mRNAs in differentiated human cells
Cytoplasmic dsRNA is recognized by RNA helicase RIG-I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), triggering induction of the innate immune response via the mitochondrial antiviral signaling protein (MAVS). In contrast, extracellular dsRNA is internalized into endosomes and rec...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6916484/ https://ncbi.nlm.nih.gov/pubmed/31615841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009783 |
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