Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE*3‐Leiden.CETP mice

Disruption of circadian rhythm by means of shift work has been associated with cardiovascular disease in humans. However, causality and underlying mechanisms have not yet been established. In this study, we exposed hyperlipidemic APOE*3‐Leiden.CETP mice to either regular light‐dark cycles, weekly 6 ...

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Veröffentlicht in:J Pineal Res
Hauptverfasser: Schilperoort, Maaike, van den Berg, Rosa, Bosmans, Laura A., van Os, Bram W., Dollé, Martijn E. T., Smits, Noortje A. M., Guichelaar, Teun, van Baarle, Debbie, Koemans, Lotte, Berbée, Jimmy F. P., Deboer, Tom, Meijer, Johanna H., de Vries, Margreet R., Vreeken, Dianne, van Gils, Janine M., Willems van Dijk, Ko, van Kerkhof, Linda W. M., Lutgens, Esther, Biermasz, Nienke R., Rensen, Patrick C. N., Kooijman, Sander
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916424/
https://ncbi.nlm.nih.gov/pubmed/31599473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12614
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