Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential

We used single‐cell RNA sequencing (seq) on several human induced pluripotent stem (iPS) cell‐derived neural stem cell (NSC) lines and one fetal brain‐derived NSC line to study inherent cell type heterogeneity at proliferating neural stem cell stage and uncovered predisposed presence of neurogenic a...

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Detalhes bibliográficos
Publicado no:Genes Cells
Main Authors: Lam, Matti, Sanosaka, Tsukasa, Lundin, Anders, Imaizumi, Kent, Etal, Damla, Karlsson, Fredrik H., Clausen, Maryam, Cairns, Jonathan, Hicks, Ryan, Kohyama, Jun, Kele, Malin, Okano, Hideyuki, Falk, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916357/
https://ncbi.nlm.nih.gov/pubmed/31651061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12731
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