Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential

We used single‐cell RNA sequencing (seq) on several human induced pluripotent stem (iPS) cell‐derived neural stem cell (NSC) lines and one fetal brain‐derived NSC line to study inherent cell type heterogeneity at proliferating neural stem cell stage and uncovered predisposed presence of neurogenic a...

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Détails bibliographiques
Publié dans:Genes Cells
Auteurs principaux: Lam, Matti, Sanosaka, Tsukasa, Lundin, Anders, Imaizumi, Kent, Etal, Damla, Karlsson, Fredrik H., Clausen, Maryam, Cairns, Jonathan, Hicks, Ryan, Kohyama, Jun, Kele, Malin, Okano, Hideyuki, Falk, Anna
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916357/
https://ncbi.nlm.nih.gov/pubmed/31651061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12731
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