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The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: systematic review and meta-analysis protocol

BACKGROUND: Pyrazinamide (PZA) is a key component of current and future regimens for tuberculosis (TB). Inclusion of PZA at higher doses and for longer durations may improve efficacy outcomes but must be balanced against the potential for worse safety outcomes. METHODS: We will search for randomised...

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Detalhes bibliográficos
Publicado no:Syst Rev
Main Authors: Millard, James D., Mackay, Elizabeth A., Bonnett, Laura J., Davies, Geraint R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915872/
https://ncbi.nlm.nih.gov/pubmed/31847921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-019-1231-1
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