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Recovering rearranged cancer chromosomes from karyotype graphs

BACKGROUND: Many cancer genomes are extensively rearranged with highly aberrant chromosomal karyotypes. Structural and copy number variations in cancer genomes can be determined via abnormal mapping of sequenced reads to the reference genome. Recently it became possible to reconcile both of these ty...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Aganezov, Sergey, Zban, Ilya, Aksenov, Vitaly, Alexeev, Nikita, Schatz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915857/
https://ncbi.nlm.nih.gov/pubmed/31842730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3208-4
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