The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans

CONTEXT: Reduced β-cell mass, impaired islet function, and dedifferentiation are considered causal to development of hyperglycemia and type 2 diabetes. In human cohort studies, changes of islet cell–specific expression patterns have been associated with diabetes but not directly with in vivo insulin...

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Veröffentlicht in:J Clin Endocrinol Metab
Hauptverfasser: Gerst, Felicia, Jaghutriz, Benjamin A, Staiger, Harald, Schulte, Anke M, Lorza-Gil, Estela, Kaiser, Gabriele, Panse, Madhura, Haug, Sieglinde, Heni, Martin, Schütz, Monika, Stadion, Mandy, Schürmann, Annette, Marzetta, Flavia, Ibberson, Mark, Sipos, Bence, Fend, Falko, Fleming, Thomas, Nawroth, Peter P, Königsrainer, Alfred, Nadalin, Silvio, Wagner, Silvia, Peter, Andreas, Fritsche, Andreas, Richter, Daniela, Solimena, Michele, Häring, Hans-Ulrich, Ullrich, Susanne, Wagner, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2018
Schlagworte:
Clinical Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915830/
https://ncbi.nlm.nih.gov/pubmed/30202879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-00791
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