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Towards Rational Computational Engineering of Psychrophilic Enzymes

Cold-adapted enzymes from psychrophilic species achieve their high catalytic efficiency at low temperature by a different partitioning of the activation free energy into its enthalpic and entropic components, compared to orthologous mesophilic enzymes. Their lower activation enthalpy, partly compens...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sočan, Jaka, Isaksen, Geir Villy, Brandsdal, Bjørn Olav, Åqvist, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915740/
https://ncbi.nlm.nih.gov/pubmed/31844096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55697-4
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